Cureus, Structural MRI Brain Alterations in Borderline Personality Disorder and Bipolar Disorder

Bipolar disorder (BD) and borderline personality disorder (BPD) share many behavioral features, such as periods of marked affective lability and instability. Although there is a symptomatic overlap, the two disorders may be differentiated based on longitudinal course, phenomenology, and treatment responsiveness. In addition, the emotional changes in BPD are generally influenced by interpersonal factors, whereas BD episodes tend to be more sustained. We performed a literature review on the structural MRI features of both disorders and compared the findings. There are differences in areas of white and gray matter volumes and thickness in BP and BPD. BPD primarily affects the fronto-limbic network, in particular, the amygdala, hippocampus, and orbitofrontal cortex, whereas BP affects both cortical and subcortical areas. There are a limited number of large studies, and many studies examined in this review did not adjust for confounding factors or motion artifacts, which limit the utility of current data.

The Neuropsychological Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Activation Likelihood Estimation Meta-Analysis of Brain Imaging Research

The Neuropsychological Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Activation Likelihood Estimation Meta-Analysis of Brain Imaging Research

Common and distinct patterns of grey matter alterations in borderline personality disorder and bipolar disorder: voxel-based meta-analysis, The British Journal of Psychiatry

Amygdala Functional Connectivity in Young Women with Borderline Personality Disorder

Bipolar disorder can be hard to tell from depression due to their similar symptoms, except for mania in bipolar. Researchers had 80% accuracy in distinguishing bipolar disorder from depression using special MRI

Cortical thickness of autistic people : r/autism

The Neuropsychological Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Activation Likelihood Estimation Meta-Analysis of Brain Imaging Research

PDF) Structural MRI Brain Alterations in Borderline Personality Disorder and Bipolar Disorder

Childhood trauma, midbrain activation and psychotic symptoms in borderline personality disorder

Cureus

Brain structure and symptom dimensions in borderline personality disorder, European Psychiatry

Brain Sciences, Free Full-Text

PDF] Structural MRI Brain Alterations in Borderline Personality Disorder and Bipolar Disorder