SARS-CoV-2 evades natural killer cell cytotoxic responses
Por um escritor misterioso
Last updated 16 fevereiro 2025
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://d2jx2rerrg6sh3.cloudfront.net/images/news/ImageForNews_717501_16559554137953577.jpg)
In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://www.mdpi.com/biomedicines/biomedicines-10-01002/article_deploy/html/images/biomedicines-10-01002-g002.png)
Biomedicines, Free Full-Text
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://criver.widen.net/content/fwzgssz8ff/gif/GettyImages-1345490871.gif?w=1142&h=500&keep=c&crop=yes&color=ffffffff&quality=80&u=8anjqk)
Could Chimeric Antigen Receptor-NK Cell Therapy Be the Next Big Thing?
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://iiif.elifesciences.org/lax/80552%2Felife-80552-fig1-v1.tif/full/1500,/0/default.jpg)
Natural Killer Cells: Taking on SARS-CoV-2
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://www.pnas.org/cms/10.1073/pnas.2208525120/asset/9fbc129d-55d4-462a-b185-70088b2f9dcf/assets/images/large/pnas.2208525120fig05.jpg)
SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://journals.asm.org/cms/10.1128/mbio.03393-22/asset/c5c0c83b-ef6b-49ac-bc42-db6b39953af6/assets/images/medium/mbio.03393-22-f007.gif)
Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://www.isct-cytotherapy.org/cms/asset/f2efa52e-8e1e-48b1-bd82-16adaf12055f/gr1.jpg)
Generating natural killer cells for adoptive transfer: expanding horizons - Cytotherapy
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://scx2.b-cdn.net/gfx/news/hires/2021/1-sarscov2muta.jpg)
SARS-CoV-2 mutations can complicate immune surveillance of human T-killer cells
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41590-018-0163-6/MediaObjects/41590_2018_163_Fig1_HTML.png)
Natural killer cell specificity for viral infections
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://journals.asm.org/cms/10.1128/mbio.03393-22/asset/3856c091-5299-41cf-b4bb-8ae2ee3da288/assets/images/medium/mbio.03393-22-f001.gif)
Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://cdn.the-scientist.com/assets/articleNo/68466/iImg/41284/uploads/03_21_sexdifferences_infogfinals.jpg)
Infographic: How SARS-CoV-2 Immune Responses May Differ by Sex
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41392-022-00907-1/MediaObjects/41392_2022_907_Fig1_HTML.png)
The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication
![SARS-CoV-2 evades natural killer cell cytotoxic responses](https://iiif.elifesciences.org/lax/74489%2Felife-74489-fig5-v3.tif/full/,1500/0/default.jpg)
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies
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