Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments: Molecular Therapy
Por um escritor misterioso
Last updated 08 março 2025


dCas9-based gene editing for cleavage-free genomic knock-in of long sequences

Cells, Free Full-Text
Multiplexed Guide RNA Expression Leads to Increased Mutation Frequency in Targeted Window Using a CRISPR-Guided Error-Prone DNA Polymerase in Saccharomyces cerevisiae

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A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement
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Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells

Evaluating the Genomic Parameters Governing rAAV-Mediated Homologous Recombination: Molecular Therapy
ACtivE: Assembly and CRISPR-Targeted in Vivo Editing for Yeast Genome Engineering Using Minimum Reagents and Time

CRISPR gene editing - Wikipedia

Efficient high-precision homology-directed repair-dependent genome editing by HDRobust

Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi: Molecular Therapy - Nucleic Acids

Specificity of oligonucleotide gene therapy (OGT) agents
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