Survival in patients with Parkinson's disease: a ten-year follow
Por um escritor misterioso
Last updated 03 abril 2025

Background A thorough understanding of the factors that influence patient survival in Parkinson’s disease (PD) will aid in prognosis prediction and provide a new direction for disease modification treatment. Currently, there are no standardized mortality ratio (SMR) data for PD patients in the northern Chinese mainland. The main focus of this study was to determine which factors in the prospectively collected baseline characteristics can affect the survival of PD patients. In addition, for the first time, we investigated the SMR of PD patients in northern China. Methods Between 2009 and 2012, 218 PD patients were continuously recruited from the movement disorder clinic of the First Affiliated Hospital of Dalian Medical University and followed up until death or May 31, 2021. The prespecified prognostic variables were demographics, clinical features, lifestyle factors, and drug dose prospectively collected at baseline. To determine the independent predictors of survival during follow-up, the Cox proportional hazards model was used. Kaplan–Meier analysis was applied to estimate the overall survival curve and to compare survival between layers based on statistically significant predictors. The SMR of this northern Chinese mainland PD cohort was calculated. Results After a mean follow-up of 9.58 ± 2.27 years, 50 patients (22.90%) died. Factors that could individually predict shortened survival during follow-up included older age at onset (hazard ratio [HR] 1.10, 95% confidence interval [CI] 1.06–1.15), Hoehn and Yahr (H&Y) stage ≥ 3 (HR 9.36, 95% CI 2.82–31.03) and severe cognitive impairment (HR 6.18, 95% CI 2.75–13.88). Univariate Cox regression revealed that a certain amount of physical activity was associated with better survival (HR 0.41, 95% CI 0.22–0.74), while fatigue was associated with an increased risk of death (HR 2.54, 95% CI 1.37–4.70). The overall SMR was 1.32 (95% CI 0.98–1.74). Conclusions Older age at onset, higher baseline H&Y stage, and severe cognitive impairment have a negative impact on survival. The 10-year survival of PD patients is not significantly different from that of the general population in China.

Parkinson's disease - Wikipedia

Recognizing the Progression of Parkinson's Disease Symptoms
:max_bytes(150000):strip_icc()/ivanastar-58a88cb65f9b58a3c9c81fba.jpg)
Life Expectancy in Parkinson's Disease

Impact of Off-Time on Quality of Life in Parkinson's Patients and Their Caregivers: Insights from Social Media

Frontiers Mortality and causes of death in patients with Parkinson's disease: a nationwide population-based cohort study

Parkinson Disease: Practice Essentials, Background, Anatomy

Behavioral Sciences, Free Full-Text
Cancer - Our World in Data

PDF) Survival in patients with Parkinson's disease: a ten-year follow-up study in northern China

Why did 250,000 Britons die sooner than expected?
Recomendado para você
-
Bronstein popular -_exames_a_preços_populares03 abril 2025
-
Gmail - Bronstein Mega Méier03 abril 2025
-
LUCRO LÍQUIDO DA NEOENERGIA SOFRE QUEDA DE 92,2% NO SEGUNDO03 abril 2025
-
Laboratório Bronstein - Mega Unidade Méier I em Méier - Laboratórios de Análises Clínicas perto de Méier, Rio de Janeiro - RJ03 abril 2025
-
Playboy Magazine 2002 September Katie Price Jordan Shallan Meiers Lenny Kravitz03 abril 2025
-
Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models03 abril 2025
-
Interesting discussion on dealmaking in Pharma industry. Thanks to #reedsmith and #milantakker., Peter Louwagie posted on the topic03 abril 2025
-
These testimonies speak for themselves. #cyberbullyingkills #donotuseyourdeviceasaweapon Nate Bronstein, forever 1503 abril 2025
-
Michael M. Bronstein · Geometric Deep Learning for computational protein design · SlidesLive03 abril 2025
-
Bronstein Medicina Diagnóstica - Méier I (Megaunidade), R. Dias da03 abril 2025
você pode gostar
-
Produto, Detalhes03 abril 2025
-
The Queen's Gambit movie review (2020)03 abril 2025
-
Fiorino arqueado: como moda polêmica dos caminhões inspirou novas03 abril 2025
-
Arturo Peniche - Wikipedia03 abril 2025
-
OS 10 POKÉMON MAIS RAROS EM POKÉMON GO!03 abril 2025
-
Erro durante o download do Google play, no momento de iniciar o jogo call of duty mobile - Comunidade Google Play03 abril 2025
-
CASA DE CAMPO - 42 Photos & 40 Reviews - 7137 Little River Tpke, Annandale, Virginia - Peruvian - Restaurant Reviews - Phone Number - Menu - Yelp03 abril 2025
-
SCP vs Marvel] Who is stronger, Scarlet King or The Beyonder(Pre03 abril 2025
-
Eles determinaram qual foi a causa da morte de Emiliano Sala03 abril 2025
-
▷ The Amazing FlyOrDie Chess Servers! - Alberto Chueca - High Performance Chess Academy03 abril 2025