Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus
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Last updated 12 abril 2025


Magnetite‐based Janus nanoparticles, their synthesis and biomedical applications - Madadi - WIREs Nanomedicine and Nanobiotechnology - Wiley Online Library

Molecules, Free Full-Text

Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat

Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat

Treating inflammation with the Janus Kinase inhibitor CP-690,550: Trends in Pharmacological Sciences

Full article: Binding selectivity-dependent molecular mechanism of inhibitors towards CDK2 and CDK6 investigated by multiple short molecular dynamics and free energy landscapes

Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat

Full article: Ligand-based and e-pharmacophore modeling, 3D-QSAR and hierarchical virtual screening to identify dual inhibitors of spleen tyrosine kinase (Syk) and janus kinase 3 (JAK3)

The role of ligand efficiency metrics in drug discovery

A ) Triaminotriazine-acridine conjugate 1 designed for selective

Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies

Recent Advances in Dual BRD4‐Kinase Inhibitors Based on Polypharmacology - Chen - 2022 - ChemMedChem - Wiley Online Library

Design, Synthesis, and Antitumor Efficacy of Substituted 2-Amino[1,2,4]triazolopyrimidines and Related Heterocycles as Dual Inhibitors for Microtubule Polymerization and Janus Kinase 2

Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat.

Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes - Gehringer - 2014 - ChemMedChem - Wiley Online Library
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