Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules
Por um escritor misterioso
Last updated 11 abril 2025


Chemical ADP-ribosylation: mono-ADPr-peptides and oligo-ADP-ribose - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C9OB00501C

Intracellular mono-ADP-ribosyltransferases at the host–virus interphase
Overexpressed PARP7 mono-ADP-ribosylates overexpressed ERα. (A) PARP7

Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner

Chemical genetic methodologies for identifying protein substrates of PARPs: Trends in Biochemical Sciences

Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes - Tim J. Wigle, W. David Church, Christina R. Majer, Kerren K. Swinger, Demet Aybar, Laurie B. Schenkel, Melissa M. Vasbinder, Arne

Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules

Poly (ADP-ribose) polymerase (PARP) inhibitors as chemosensitizing compounds for the treatment of drug resistant cancers

Medicinal Chemistry Perspective on Targeting Mono-ADP-Ribosylating PARPs with Small Molecules

Frontiers Research Progress on Mono-ADP-Ribosyltransferases in Human Cell Biology

Human Poly (ADP-ribose) Polymerase Family Member 14 (PARP14)

PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis

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